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This article highlights 20 in-house legal leaders who have made an important contribution in helping their organisations respond to a wide range of business challenges. Among them, Joel Unruch from Accenture has been preparing the business for generative AI’s impact. He worked closely with Ray Eitel-Porter to identify and categorise the potential uses of this technology in the business and also to mitigate its risks. Brian Israel from Microsoft has been leading the company’s efforts to ensure that AI is used responsibly and ethically.