This Special Issue examines the latest progress and new methods on artificial intelligence and robotics, which provide intelligent processing of large volumes of fuzzy information in operational environments. It covers mathematical models, algorithms and software, hardware control of robots, unmanned aerial vehicles, and their built-in and attached equipment. The goal is to automate information, physical, and energy interactions of heterogeneous robotic and cyber-physical systems. Manuscripts should be submitted online by the deadline and accepted papers will be published continuously in the journal.