Mhc-i Upregulation Safeguards Neoplastic T Cells In The Skin Against Nk Cell-mediated Eradication In Mycosis Fungoides

This article discusses a clonality-guided deep learning approach to identify genes with predictive value for cancer in skin tumor T cells. The study used single-cell RNA sequencing to analyze T cells from MF skin lesions and blood of MF patients, as well as T cells from healthy individuals. The results showed potential for predicting disease-specific clinical outcomes at the individual T cell level.