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This article discusses the use of machine learning algorithms to identify important anthropometric factors that may predict hypertension (HTN) in adults aged 35-65 years. The study was conducted in northeastern Iran and included 9704 participants. Blood pressure was measured using a sphygmomanometer and HTN was determined as systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90. Logistic regression (LR), decision trees (DT), and bootstrap forest (BF) were applied to find the most important anthropometric factors that may predict HTN.