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This article discusses the use of machine learning to diagnose and predict Alzheimer’s Disease (AD). It proposes a novel deep learning model based on a group of Long Short-Term Memory (LSTM) base classifiers to interpret time series data collected from the National Alzheimer’s Coordinating Center (NACC) dataset. This model is designed to accurately predict AD based on a collection of cost-effective multivariate time series data and uses the Bayesian optimizer technique to build an optimal deep stacking model.