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Bioengineers are utilizing rapidly evolving machine learning tools, deep data reservoirs, and AlphaFold2 to pursue more sophisticated de novo protein designs. AlphaFold2 is an algorithm developed by DeepMind that can predict protein structures based on amino acid sequences. This ML toolbox is capable of generating made-to-order proteins with functions not present in nature. Companies are focusing on retooling existing proteins to perform new tasks or enhance specific properties, rather than true design from scratch.