Deep Learning For Predicting 16s Rrna Gene Copy Number

A deep learning-based bioinformatic tool, ANNA16, was developed to interpret DNA sequence information and correct 16S GCN data. The tool was evaluated against current 16S GCN correction tools and trained on 16S full-length DNA sequences from rrnDB. An ensemble model of MLP and SVM was selected and compared to traditional taxonomy and phylogeny-based algorithms.