The use of Artificial Intelligence (AI) in programmatic advertising is becoming increasingly important in the cookieless era. Advertisers and publishers are utilizing AI tools to deliver personalized and hyper-targeted ad experiences to a larger demographic across various platforms. This has led to a predicted $1.3 trillion spending on AI-powered advertising campaigns and software in the next 10 years. AI is used in four main areas of programmatic advertising, with personalization emerging as a fifth element. Adtech executives discuss the current state of paid media activation and personalization in the cookieless era.