This article discusses the introduction of a new course at Caltech, EE/CS 148: Large Language and Vision Models, which focuses on generative AI technology. The course is taught by Georgia Gkioxari, an assistant professor of computing and mathematical sciences and electrical engineering, and Pietro Perona, a professor of electrical engineering. The course provides students with an opportunity to learn about the leading edge of generative AI technology and how to use it for their own purposes.