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This article discusses the use of assistive robots (AR) to support the process of care giving, with the potential to enhance patient well-being and decrease caregiver workload. It also focuses on the Human-Robot Interaction (HRI) field, which is devoted to understanding, designing, and assessing the robotic systems used by humans. Research in the HRI field is increasingly focused on the development of robots equipped with intelligent communicative abilities, in particular speech-based natural-language conversational abilities. This Special Issue will focus on advancing novel technologies applied in healthcare processes that have shown exceptional promise in models of HRI through the use of new sensors or methodologies.