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In a recent experiment published in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) tested the ability of a publicly available chatbot, Chat-GPT 4, to make accurate diagnoses in challenging medical cases. The team found that the generative AI chatbot selected the correct diagnosis as its top diagnosis nearly 40 percent of the time and provided the correct diagnosis in its list of potential diagnoses in two-thirds of challenging cases. The experiment was conducted using clinicopathological case conferences (CPCs), a series of complex and challenging patient cases including relevant clinical and laboratory data, imaging studies, and histopathological findings.