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The fields of artificial intelligence (AI) and genomics have experienced increased public attention and investment in recent years. AI and genomics have been used to address major scientific challenges, but have also resulted in ethical and societal implications. AI and genomics are becoming increasingly intertwined, with AI being used to make advances in genomics and genomic data being used to create AI-powered products. This convergence is set to present policymakers with a new set of challenges, as both fields already pose deep questions concerning agency, privacy, quality, bias and power.