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Japan’s Action Plan of Growth Strategy, which was set out 10 years ago, declared initiatives of digitalization for medicine, nursing care, and healthcare to achieve the world’s most advanced medical care. This article thoroughly describes Digital Therapeutics (DTx) in Japan and compares it with those in the US and Germany. Two of three DTx applications that have been approved and reimbursed by the Ministry of Health, Labor, and Welfare are explained in detail in relation to cardiovascular medicine. DTx in cardiovascular medicine, with consideration on safety, efficacy, and cost-effectiveness, could be widely used not only through basic experiments and clinical studies but also through social implementation.
