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This article looks at the top 5 healthcare data science projects that are shaping the future. These projects include AlphaFold, a deep-learning model developed by Google’s DeepMind that aims to solve one of the most challenging problems in biology – protein folding; Microsoft’s InnerEye, a machine learning-based project that focuses on medical image analysis; Project Inner, a deep learning-based system developed by Alphabet subsidiary DeepMind that can detect and diagnose diseases from medical images; IBM Watson, a cognitive computing system that can help healthcare professionals make more informed decisions; and Google Health, a platform that enables healthcare professionals to access and analyze patient data.